's symptom of cause of disease of gastric carcinoma

's symptom of cause of disease of gastric carcinoma
The cause of disease of cancer has not been totally expounded yet so far. Through studying to geographical distribution and relation with immigrant that gastric carcinoma has illness coming on, it is generally acknowledged the external environment is in most close relation with diet factor and emergence of gastric carcinoma, the human body has some conditions of facilitating gastric carcinoma taking place, can not ignore either.
(1) Inherent cause Clinical workers have all met two or more in a family
Member with gastric carcinoma for situation,such and good inclination of sending gastric carcinoma is though getting more rare very, but briefed on the possibility with the inherent cause at least. Have of relative that materials report the gastric carcinoma patient the morbidity of gastric carcinoma is 4 times higher than that of the control group.
In the inherent cause, many authors notice the relation of blood group. Someone counts, the A type person's morbidity of gastric carcinoma is higher by 20% than the person of other blood group. But the gastric carcinoma incidence of the person who thinks different blood group of some reports has no difference. Someone studies the relation of morbidity and H L A of gastric carcinoma, wait to further conclude in recent years.
(2) The survey of epidemiology respect of gastric carcinoma of countries all over the world of the geographical environmental factor shows, the obvious difference exists in different areas and ethnic morbidity of gastric carcinoma. These differences may relate to heredity and environmental factor.
Some materials prove gastric carcinoma occur frequently in Yu GaoWei one degree of areas, the country the farther from the equator, the higher the morbidity of gastric carcinoma is. Also there are materials that think it has illness coming on and relates to coastal factor. Here's the factors of different eating habits, should consider too that the possibility of the carcinogen exists in geochemistry factor and environment.
The national gastric carcinoma integrated survey epidemiology group has investigated the domestic gastric carcinoma hotspot, for instance ground such as the Hexi Corridor, upper reaches of the Yellow River, the Changjiang River low reaches, Fujian Jiangkou, wooden Lanxi low reaches and Taihang Mountain south segment of the river system of Qi LianShan's indraft, find except that the south segment of Taihang Mountain is the metamorphic rock, the others are the volcanic rock, high peat, or one side its have big fault dark, C a/S O 4 little ratio under water, nickel, selenium and get into content to be high. Study group investigate gastric carcinoma to be low to send area, the intersection of the Changjiang River and upstream and the intersection of Pearl River and river system and other places still, find this district is the limestone area, without big deep fault, C a/S O 4 ratio is big in water, nickel, selenium and cobalt content are low. Containing 3 in the known volcanic rock, 4 benzene combines Zhyuan, some were up to 5 unexpectedly. 4- 6. 1 g/k g, forebody's content of inferior nitre amine such as organic nitrogen are relatively high in the peat, makes the mucous membrane of stomach incident and damages. In addition, selenium and cobalt can cause the stomach to damage, nickel can promote 3, the carcinogenic function of 4 benzene and Zhyuan. The above geographical environmental factor, in order to form the reason of these domestic gastric carcinoma hotspots, worth further exploring.
(3) The diet factor diet factor has already been paid attention to by tumour research workers of various countries to the influence that gastric carcinoma has illness coming on. Possible the intersection of diet and carcinogenic factor for eat smoke, roast the intersection of roast meat and food often ' Includes benzene and combine Zhyuan) Or pickle food, pickled vegetable ' Includes N - inferior nitre base compound) . The research in recent years has proposed to protect the factor, such as milk, animal's albumen, fresh vegetables and some fruits,etc.. The decline of Japan and American gastric carcinoma morbidity has been belonged to the improvement of the diet situation recently. But the relation of diet and tumour and research of carcinogenic mechanism are extremely complicated. There may already be carcinogen playing a direct role in the food, no matter exist naturally or produce while the food is cooked, processed, preserved; May form carcinogen in the body under some factor function too behind the human body of food intake. In the carcinogenic course, some materials play a role in starting carcinogen, some play a role in urging cancer or restraining cancer, and interweave with the complicated supersession, bio-transformation course in the human body together, so it is very difficult to find the definite connection from these complicated factors. The experiment materials can be used for appraising the diet and function in human gastric carcinoma take place of supersession factor, when its result conforms with epidemiology evidence, its result is convincing.
The integrated survey epidemiology group of gastric carcinoma of our country shows gastric carcinoma in close relation with diet to the high, investigation result of the low having illness coming on area of domestic gastric carcinoma. In variegated aspergillus toxin brings out the experiment of mouse's hepatocarcinoma of coming out, have seen the emergence of gastric gland cancer. Can detect variegated aspergillus and construct fungi such as aspergillus of the nest,etc. from main non-staple food and the patient's gastric juice of the survey district, the detection rate of the gastric carcinoma hotspot is obviously higher than taking place to the area low, it is a dangerous factor related to gastric carcinoma to brief on the mould grain.
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