Sunday, December 2, 2012

The new means living beings of gastric carcinoma treatment treat _'s treatment

The new means living beings of gastric carcinoma treatment treat _'s treatment
The treatment of gastric carcinoma has already made considerable progress in recent years, surgery, radiotherapy, chemotherapy form three major modes of tumour. But the therapeutic method is often difficult eliminates tumour cells completely, and apt to damage the normal tissue, especially injure the immune system occupying the important position in the antitumor defence of organism, especially influence the cell immunity. Under modern molecular biology and push that the genetic engineering develops at full speed, based on immunization therapy biological treatment of development, receive, pay attention to day by day, demonstrate good application prospect, become the fourth mode of tumour treatment.
The biological treatment includes:
The factor technology of cell: IFN, IL, TNF, CSF, TGF,etc.;
Adopt the technology of immunization therapy: LAK, TIL, CTL, CIK,etc.;
Monoclonal antibody and uniting biotechnology occasionally : Namely " biological guided missile " Treatment;
The technology of vaccine of tumour: DC cells;
Gene therapy: P53,etc..
Clinical practice at present most CIK cell or CIK +DC cell treatment.
CIK cell treatment suitable for every one of gastric carcinoma: The postoperative whole body of effecting a radical cure of early gastric carcinoma is immune, defend recuring; Can't excise or condone patient can adopt CIK cell treatment jointly complex treatment such as chemotherapy are set free later period in the excise, lengthen life cycle, improve life quality.
The therapeutic clinic of CIK cell summarizes to reveal: 53 accept and digest in CIK cell treatment in department's tumour patient in later period, PR +MR is 39, always the relieving rate is 73.6%, survival rate is 92.4% to follow up a case by regular visits to one year, it was 83.0% in 2, it was 75.5% in 3. There is obvious improvement (Plt before and after treatment in clinical symptom; 0.05); The improving rate is 79.24% that the quality card grades to survive; Treating front and back CD4, CD19, CD3/CD16 +CD56 difference has a statistics meaning (Plt; 0.05); The tumour mark CA199 difference has statistics meanings (t =7.91Plt; 0.05); Most of weight have increase.
In sum: CIK cells, to the operation, can offer one kind of lengthening life cycle, new route to improve life qualities to digest department's tumour patients in later period in the card radiotherapy, chemotherapy have not met yet.
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