From what reason was the lung song fungus disease caused? 's general knowledge

From what reason was the lung song fungus disease caused? 's general knowledge
From what reason was the lung song fungus disease caused?
The song fungus ball is the most common type. Song fungus depend on for a living on pulmonary tuberculosis, the intersection of bronchus and the intersection of lung and cyst, lung cancer and the intersection of tubercle and disease,etc. in the chronic the intersection of lung and cavity that disease form often. The cavity wall and lung tissue around destroy partly, alveolus internal haemorrhage, a large number of chronic inflammatory cells soak with a lot of small outgrowth arteries, veins, present the tumour kind expanding, generally there is not hypha that is invaded. There are yellowish-brown balls in the hole, relatively crisp, the tangent plane has pigmentation, the ones that includes into a pile separate branched myceliums, mixed with having a liking for acid amorphous material and erythrocyte in a large amount. It is applied with the union of the allergy that ABPA is. The short chain song fungus spore sucked falls into in bigger segment bronchus secretes the mucus, form the mycelium; Antigen with IgE its cause quick to roll over loose cell take place specificity combine, release medium, cause bronchospasm, the penetrating increase of mucous membrane of bronchus, the antigen enters the tissue, cause acidophil in lung and blood to increase. In addition, the fungus antigen of song binds with IgG antibody and forms the immune complex, cause the bronchus and lung around to organize chronic inflammation under the participation of complement, cause bronchus destroying, expand and the lung fiber. Bronchus wall and lung essence are acidophil and monocyte soaking and granulation swollenly and take shape, in charge of there is fungus hypha of songing, but there is not hypha that invade the tissue. IPA sees in chronic consuming disease, fungus one group of lacking proper care, immunological functions reduce a patient. The intersection of song and fungus that depend on for a living in the upper respiratory tract invade the lung to organize, develop into necrosis nature bleeding pneumonia, can cause and suppurate, it is swollen to form multiple abscess or granulation, there is arteriolar thromboembolism on the edge of focus. The song fungus invades the lung blood vessel to lead to the fact the blood walks and sows scatteredly, involves the other internal organs of whole body.
Which lung song fungus disease are to behave and how to diagnose?
Clinical manifestation
The song fungus ball patient does not have obvious whole body symptom, but favorable hemoptysis and coughing. The isolated crescent type ball type cooking stove of bright district in the lung, behave for its typical X type.
ABPA takes place specially in conformity with the physique foundation of the sex generally, takes the form of persons who break out repeatedly and wheezes, generates heat, coughs, expectorates the brown phlegm bolt, spits blood. Two lungs of physical examination are covered with the sound of chirping of heavy breathing, the lung soaks the position there is a thin wet rale. The chest X-ray shows the lobe of the lung, one section of infiltration focuses distributed, often in order to visit the going; The intersection of lung and consolidation, or because the intersection of mucus and the intersection of thromboembolism and bronchus cause the intersection of lung and section or the intersection of lobe of the lung and piece, have, split, shift among the leaf, it can cause bronchiectasis in the centre to break out repeatedly for a long time, the segment or inferior section of bronchuses given much trouble takes the form of the bag to expand, and correct it often far. Shade such as car rail thread kind, parallel, ring-type, banding or toothpaste kind, meaning one set of forms can often also be seen. Acidophil of blood increases. Serum IgE density rises. Song the intersection of fungus and extract make skin, test, can present pairs of phase, react inside: Unless after it test by 15-20 minute, it appear, wind group and blush react,can't disappear about 0.5- 2 hour (type react) ; 4- Observe again 10 hour, it is react Arthus not to last part at cover,it disappear about 24- 36 hour (type react) . The patient includes the fungus -specific sediment of the song plainly, determine with the serum sample concentrated, the positive rate is up to 92%.
IPA patient is badly sick. There is generating heat, cough, coughs suppuration phlegm, chest and aches, spits blood, has difficulty in breathinging, and it is scattered to sow corresponding symptom and physical sign caused to other organs. The physical examination finds the lung there are doing, wet rales. The X-ray is early can present limitation or one pair of lungs occuring frequently infiltration, or tubercle shade, the focus is often expanded and merged to turn into necrosis and form the cavity in fact rapidly; Or the great, Tenneco, base happens to the shade to the pleura suddenly, similar to " The gentle one " The lung blocks up. Minority present the thorax to store up the liquid sign.
Diagnosis
Suck the secretion out of deep department of bronchus, the slide finds the hypha, it is positive to train many times, contribute to diagnosing. Diagnose meanings in X-ray characteristic that the coccus of song is typical. Song the intersection of fungus and antigenic skin test with serum precipitating and testing the masculine gender and diagnosing value inside. The intersection of bronchus and asthma, around the intersection of blood and the intersection of acidophil and increase, serum of breaking out etc. IgE raise and X-ray show the lung soak the cooking stove, prop up the mirror to suck out of the secretion slide and have fungus hypha of song through being fine, or train song fungus and grow, can diagnose as the bronchus lung song fungus disease of allergy. Perspect, down, make a reservation by fine to prop up mirror, make lung, live, examine, make a definite diagnosis of value.
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