's general knowledge of disease pathogenesis of song fungus of the lung

's general knowledge of disease pathogenesis of song fungus of the lung
The song fungus ball is the most common type. Song fungus depend on for a living on pulmonary tuberculosis, the intersection of bronchus and the intersection of lung and cyst, lung cancer and the intersection of tubercle and disease,etc. in the chronic the intersection of lung and cavity that disease form often. The cavity wall and lung tissue around destroy partly, alveolus internal haemorrhage, a large number of chronic inflammatory cells soak with a lot of small outgrowth arteries, veins, present the tumour kind expanding, generally there is not hypha that is invaded. There are yellowish-brown balls in the hole, relatively crisp, the tangent plane has pigmentation, the ones that includes into a pile separate branched myceliums, mixed with having a liking for acid amorphous material and erythrocyte in a large amount. It is applied with the union of the allergy that ABPA is. The short chain song fungus spore sucked falls into in bigger segment bronchus secretes the mucus, form the mycelium; Antigen with IgE its cause quick to roll over loose cell take place specificity combine, release medium, cause bronchospasm, the penetrating increase of mucous membrane of bronchus, the antigen enters the tissue, cause acidophil in lung and blood to increase. In addition, the fungus antigen of song binds with IgG antibody and forms the immune complex, cause the bronchus and lung around to organize chronic inflammation under the participation of complement, cause bronchus destroying, expand and the lung fiber. Bronchus wall and lung essence are acidophil and monocyte soaking and granulation swollenly and take shape, in charge of there is fungus hypha of songing, but there is not hypha that invade the tissue. IPA sees in chronic consuming disease, fungus one group of lacking proper care, immunological functions reduce a patient. The intersection of song and fungus that depend on for a living in the upper respiratory tract invade the lung to organize, develop into necrosis nature bleeding pneumonia, can cause and suppurate, it is swollen to form multiple abscess or granulation, there is arteriolar thromboembolism on the edge of focus. The song fungus invades the lung blood vessel to lead to the fact the blood walks and sows scatteredly, involves the other internal organs of whole body.
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