Friday, July 27, 2012

Mechanism's _ general knowledge of cause of disease and having illness coming on of the lung bead fungus disease

Mechanism's _ general knowledge of cause of disease and having illness coming on of the lung bead fungus disease
First, pathogenic factor
Up until now, have already found that there are more than 270 kinds of bead funguses, among them cause mankind's pathogenic bead fungus to mainly have white bead funguses (C.albicans) , tropical bead fungus (C.tropical) , false tropical bead fungus (C.pseudotropicalis) , near smooth bead fungus (C.parapsilosis) , one gram of gentle bead funguses(C.kruseii) , star-shaped bead fungus (C.stellatoidea) , smooth bead fungus (C.glabrata) , the bead fungus (C.guilliermondii) in it is high ,It is a condition pathogen, among them have the strongest virulence with white bead fungus, the most common too. The intersection of bead and fungus grows at ordinary culture medium very fast, grow cells for the ellipse bud, form the hypha on special culture medium. The differentiation of the bacterium needs to rely on biochemistry to test.
Pathogenic strength and fungus bodily form attitude and sticking ability relevantly of the bead fungus, the yeast type seldom causes a disease, the hypha type is pathogenic. It is also strong to stick the pathogenic strength of bead fungus with strong strength. Some bead funguses can secrete toxin and hydrolase, destroy the tissue.
Normal people's skin, oral cavity, gastrointestinal tract,etc. have bead funguses to depend on for a living, do not cause a disease under the normal situation, defend function, drop as human immunity, send bone can invade the respiratory tract, cause the getting endogenous infection on oral cavity, the intersection of bead and fungus of upper respiratory tract. The diet is not clean, cross infection can cause the other source infection in the courtyard. Hold conduit, mucous membrane ulcer,etc. and destroy the integrality of mucous membrane, can also make the bead fungus invade in the body. The lung can be the primary infection, can also sow a part of the scattered bead fungus for the blood source.
Second, have illness coming on in the mechanism
The intersection of bronchus and the intersection of lung and the intersection of bead and the intersection of infection and mainly for suck route, fungus of disease ,Namely field planting sucks in the bead fungus of oral cavity and the upper respiratory tract due to lower respiratory tracts and alveoluses when the organism defends the mechanism to weaken. The bead fungus is transferred to a hypha type after invading and organizing, breed in a large amount, the hypha bead fungus resists and engulfs ability, cause the leucocyte to soak reflecting, form ulcer, occuring frequently small abscess and organize necrosis for the acute inflammation of the main fact. Chronic and infects and organizes hyperplasia with swollen pathological change of the granulation and fiber. It is the hypha that the blood source is sown scatteredly type and yeast is invaded in the blood vessel, cause one pair of lungs filling the air damage for being main, the model is shown as the lung of necrosis bleeding tubercle that the bead mushroom organized and bred in a large amount makes up.
The cell immunological function is low, use antibiotic of wide table in a large amount for a long time, employ glucocorticoid and immune inhibitor, it is risk factors to put intravenous intubate and viscera conduit for a long time.
A cell reduces, organ transplant, employing cortical hormone, diabetic's blood source incident to sow scatteredly for a long time.
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