Behavioral _'s general knowledge of cell that tumour spreads

Behavioral _'s general knowledge of cell that tumour spreads
Mechanism of metastasis of cancer of stomach
Tumour is spread including tumour is soaked ' Soak and attack) And transfer process, soak the direct diffusion which means tumour cells, from send position organize into interval, lymphatic vessel, blood vessel, coelom, cerebrospinal or organ, organization spread, involve the corresponding organ at a distance to nearby constantly originally, this inevitable stage of malignant tumour in the growth course often, neck the icy pelvis appears after the metabasis of cancer such as palace, cancer of the esophagus invades and the aorta, trachea, bronchus, lung and mediastinal, etc.
Shift, mean malignant tumour cell break away from, send tumour subject originally, with send tumour link and far the intersection of position and histoorgan continue one or more tumours sprouted to take place originally, and organize the type to be basically the same in this tumour that grows newly and pathology that sends tumour originally, have lymphs, blood vessel, plant etc. in route to shift.
The factor influencing tumour to spread relates to activity of the cancer cell, division intensity, include DNA content, cell wither die, original the intersection of cancer and activation of gene, restrain the intersection of cancer and inactivation, the intersection of cell and the intersection of mark and the intersection of characteristic and power, the intersection of hormone and high or low prices of competence,etc. of thing of gene mainly.
If measure to primary tumour in early days and excise before it spreads, then cancer can be cured. On the contrary, if has already had small transformation tumour in diagnosis, then its prognosis is serious. If refuse to treat, these shift tumour and proliferate and cause people in the fatal position extensively.
Though it is well known that tumour spreads serious consequences caused, make little progress to the process of cognition that tumour spreads. The gratifying one is that some links of studying in spreading the course in recent years have already obtained some valuable materials, among them it is not chancy that the most important discovery is spread, but an extremely active course. Namely tumour cell soak health in, organize it is one that include the intersection of cancer and cellular reaction already, include the complicated phenomenon of normal cellular reaction again.
" shift " A word was in its " cancer research " in 1829 by a French doctor JC Recamier at first Thesis in put forward,he from dissecting angle prove whether shift there are since blood circulation, lymphocytic to if you can't operate, initiate organism cancer cells at position other on tumour. Announce to latest research that spread tumour invasion of cell it shifts to be one more than step, multifactor physiological course of complex that participates in.
Cell behavior that tumour spreads
While tumour cells shift, there are a few to break away from tumour cells sending the position originally, namely being less than 1/10000 can survive and begin to form new tumour group. Tumour offers the new blood vessel in order to nourish its body of tumour spread rapidly to grow, let out because of blood vessels formed within tumour, so the cancer cell is very apt to cross wall of these blood vessels. Tumour blood vessel each branch of tree whether the intersection of tumour and cell enter potential position of circulatory system in the body.
The lymphatic vessel is the exit thoroughfare of the cancer cell too, but tumour will not produce one's own lymphocytic network. Because the lymphatic vessel should usually get rid of the surplus liquid among cells, lack the lymphatic vessel and may close the fragile blood vessel in tumour, capture oxygen of a part and nutriment of the tumour piece and damage tumour, it is useful to organism. Tumour lack lymphatic vessel, mean cancer cell can only the intersection of interface and between tumour cell and constellation chief cell enter the lymphocytic system still in the piece.
Break away from, send tumour of position originally in intravenous and lymphatic vessel run circulate, usually, until blocking the capillary bed or lymph node, or adhere to the inside lining managed. In form, continue take place tumour, mostly flowing through the heart the intersection of tumour and cell that shift, lung many kinds of common organ that tumour shift, in send blood circulation to whole body, want, pass capillary of lung first heart. Transformation cancer produced by cancer of colon usually appears in the liver, because the liver should accept the intravenous blood from large intestine directly. Shift the organ that tumour take place, it is expected, because tumour cells have not found its suitable condition that has survived, including growth factor, factors such as the albumen,etc. of hastening to melt. Most tumour cells which are held up in the capillary or lymph node will die. It may be a defensive attack of machinery vortex or host because in circulation. But within 8- 24 hours, a few tumour cells surviving begin to invade the blood vessel wall and stay in the circulatory system finally.
Not all tumour cells which enter the organ can survive and grow, only those tumour cells that begin to be bred may set up a new tumour colony. Many kinds of stimuli in the environment stimulate the hyperplasia of tumour, including growth factor which the host produced, growth factor that hormone and tumour cells produced. Tumour formed newly forms the blood vessel and offers the continuation of assurance tumour of nutrition to breed in the body. Continue the new birthplace where taking place tumour can be spread as tumour cells, so the cluster shifted can be shifted oneself, thus accelerate the deterioration of the condition.
By the end of the 70 s, someone think tumour it spreads to be one passive course, tumour cell grow pressure push into, circulate, they separate and spread in circulation each other, but this kind of hypothesis can't explain why benign tumour can't be spread. The research for the future proves, it is a initiative course that tumour is invaded, malignant tumour is mostly potential transformation tumours, it needs to invade other organizations. Have not invaded benign tumour of the characteristic and organized the demarcation line to be clearly demarcated normally around, but very difficult resolution of demarcation line of malignant tumour. The tumour cells lying in this kind of demarcation line break away from its primary tumour piece actively. The function factor of the two of invading the intricate biochemical activity in the front and including coming from tumour cells and the host happens.
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