New hope of tumour treatment

New hope of tumour treatment
Through the efforts for many years, the scientist of our country adopts the genetic recombinant technique, has succeeded in setting up a kind of new antigen -specific killer cell, this kind of cell can produce and secrete the immune toxin for a long time, kill tumour cells effectively. At present, this research is being declared to the related departments in order to carry on the clinical trial. This achievement had studied for many years and obtained by Yang AnGang, professor of fourth army medical university, and colleague of he. Yang AnGang is now " The the Changjiang River scholar rewards the plan " Professor invited specially, he go the the intersection of Buddha and the intersection of Rest and the intersection of university and medical college, North Carolina State of U.S.A., engaged in the research of gene therapy on 1995. Yang AnGang,et al. has proved T lymphocytes can produce and secrete the immune toxin for the first time in the world, growth and function of cells are normal at the same time. On the basis of this discovery, they utilize the genetic recombinant technique, will discern the antibodies and toxin molecules (PE40) of the genetic product HER-2 of cancer Genetic connection construct out the immune toxin gene together. Then channel such immune toxin gene into T lymphocytes training the body, make these T lymphocytes produce and secrete the immune toxin constantly, taking shape has cell immunity and humoral immune characteristic concurrently, and can kill the new killer cell of tumour cells effectively. In experiment, they inject the antitumor specific killer cell after the little mouse of year tumour is in the body, the immune toxin that these cells secrete can be discerned and entered within tumour cells, kill tumour cells effectively, make the growth of tumour obviously inhibited. Year the intersection of tumour and little mouse to carry on experiment behind injecting this kind of killer cell, all survive in 3 months, and the little mice of control group all die within two months. Such specific killer cell not merely can live in the body memory for several months -long time, and can circulate and get back to the lymph node and horbor constantly, wounding function bigger of cell of those tumours that can't remove and shift to the operation. It is introduced, they still train the specific killer cell which resist the defective virus of human immunity by same means, they can succeed in killing the defective virus of human immunity and infecting cells in the experiment too, inhibit and prevent the reproduction of the virus. World authoritative sexology periodical Britain's " Nature " and " natural biotechnology " publish the research thesis of this achievement, as to this has introduced the overall one.

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