What does it have to do with pulmonary tuberculosis and lung cancer? 's general knowledge
Tuberculosis is a chronic infectious disease caused by branch bacillus of tuberculosis, can involve a plurality of organs of whole body, but the pulmonary tuberculosis is the most common. Can spread and hide for a long time to whole body, have illness coming on when organism resistance is reduced, the pathologic characteristic of this disease is tuberculosis and tubercle and cheese and a kind of necrosis, it is apt to form the cavity. Though nearly two has been over the past thirty years, the morbidity has obviously dropped, it is still one of the common chronic infectious diseases occuring frequently at present.
Lung cancer (Lung.Carcinoma) It is one of the common malignant tumour, morbidity and mortality of lung cancer all have the tendency to obviously increase in near decades.
Two main respects of the relation between pulmonary tuberculosis and lung cancer: Interference diagnosed to lung cancer when indirect facilitation and active tuberculosis and lung cancer that namely pulmonary tuberculosis takes place to lung cancer are compatible.
Indirect facilitation that first, pulmonary tuberculosis happen to lung cancer
Clinical the intersection of scientific research and materials up until now brief on, though pulmonary tuberculosis will develop into lung cancer directly, but it can promote the emergence of lung cancer indirectly. Pulmonary tuberculosis mainly shows to the promotion that lung cancer takes place:
1,Pulmonary tuberculosis causes the chronic damage to the lung, has influenced the bronchus to affix leather normal function and antiviral state of immunity of organism, there is indirect facilitation on emergence of lung cancer.
2,The intersection of pulmonary tuberculosis and focus of calcification, tuberculosis cicatrix, getting outmoded the intersection of cavity and wall and their bronchus, leather the intersection of cell and hyperplasia, hyperplasia,etc. relate with the emergence of lung cancer at the alveolus.
In addition, have and find the case that outmoded pulmonary tuberculosis amalgamates lung cancer clinically frequently, further briefing on pulmonary tuberculosis has facilitation to lung cancer.
Second, active tuberculosis and lung cancer coexist, make the diagnosis of lung cancer more difficult
At present, cause of disease and pathological foundation that pulmonary tuberculosis and lung cancer coexist have not been totally expounded at present, mainly have the following views:
1,Pulmonary tuberculosis patient become more and more the old age increase with the morbidity of lung cancer severely, make the chance that the two coexist increase, it is a opportunity coincidence.
2,Most experts think tuberculosis cicatrix cause the possibility of lung cancer to be relatively great, some tuberculosis amalgamates postoperative pathology of the patient of lung cancer to brief on: There are continuity signs in hyperplasia of cover and cancer nest on the detailed bronchus in tuberculosis and cicatrix are organized, this discovery has very important meaning on explaining erupting.
3,Someone think lung cancer patient it amalgamates tuberculosis to be because tumour or because tumour put chemotherapy,etc., it causes due to tuberculosis activity to damage host's immune mechanism.
And when pulmonary tuberculosis and lung cancer coexisted, can because cytologic to find tubercle bacillus and ignore existence of lung cancer check, in focal existence or phlegm in tuberculosis often. If pulmonary tuberculosis patient, the possibility that should highly watch out for lung cancer when there are the following situations.
1,The male patient over 40, and smoke in the history for a long time.
2,Already steady pulmonary tuberculosis or in resist consumptive disease in the course while being regular the intersection of active tuberculosis and patient, symptom not in conformity with focus appears, such as the irritation coughs, take the blood in the phlegm, the chest with fixed and obstinate sore spot aches, there is not generating heat of clear inducement (even hyperpyrexia) And going on symptom of becoming thin etc..
3,X Line chest slice see lump show in round and group blocky, diameter greater than 2 - 4 C M, lump take the form of divide into foliately, edge abnormality is presented the burr kind, not with enlargement of lymph nodes and lung of lung door one.
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