Vaccine of tumour is expected to be used for treating and forming _ general knowledge of rectal cancer
The intersection of Stanford University and researcher, California of U.S.A., report one new vaccine design until 4 later period form rectal cancer, it makes to be totally disappear or the intersection of condition and steady result in the patient. In addition, a patient in the preliminary test has no cancer state to nearly last one year.
The main member Lawrence Fong doctors of this research tell conferees at the annual meeting of the clinical oncological association of U.S.A.: " the intersection of we and the target of vaccine molecule in rectal cancer of forming, the intersection of cellule and common cancer embryo antigen (CEA) under lung cancer and breast cancer . In this I/II stage test, our key research forms rectal cancer and lung cancer. All patient that participation test whether traditional chemotherapy fail later period the intersection of cancer and patient. "
12 patients in the test increase the arborescent quantity of dashing for ward cells through the way that hematopoietic growth factor FLT-3 match the body first. Then it gathers patient these to be arborescent to dash for ward cell, hatch, breed with excessive the intersection of CEA and antigen after concentration. Regard these cells as vaccine of cell and pour into patient's body again subsequently.
After inoculating vaccine, 2 patients present tumour to disappear, another 2 patient's conditions can be stabilized. One of these appear patient that tumour disappears keep not having cancer state for more than one years, another one recurs after 10 months. There is no side effect correlated with obviously treating.
Dr. Fong says: "What we find to adopt FLT3 mix physical stamina, increase tree of patient these, dash for ward form cells, it is easy to gather these cells to make into vaccine of tumour. Accept compared with patient not accepting FLT3 person who matches body, the internal tree dashes for ward form cells to increase by 50 times, thus can get more effective vaccine. We find vaccine inoculation induce and produce T cells which kill tumour. "
Dr. Fong emphasizes: "The hope of this research can treat the early cancer patient especially through making more effective tumour vaccine, or can get up and prevent disease to adopt vaccine instead of the result of treating disease. "
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