Causing _'s general knowledge of lung source heart disease

Causing _'s general knowledge of lung source heart disease
Chronic lung source heart disease (chronic cor pulmonale) Abbreviated as lung worry, it is by chronic lung disease, lung vascular disease and thoracic movement obstacle disease cause the lung to circulate resistance increase, the artery pressure of lung increases, the right ventricle is plump and expanding for heart disease of the characteristic.
Cause of disease and having illness coming on in the mechanism
1.Bronchus, the intersection of lung and disease erupt getting obstructive most common pulmonary emphysema simultaneously with chronic bronchitis, account for 80% - 90% , Secondly for the intersection of bronchus and asthma, bronchiectasis, pneumoconiosis, the intersection of quality and the intersection of fiber and take, chronic the intersection of fiber and empty pulmonary tuberculosis, the intersection of tubercle and disease,etc. under lung of filling the air etc.. Keep in touch with the function obstacle, destroy protective screen of qi and blood of the lung in blockade that these diseases cause, reduce the gas-exchange surface, cause the disperse obstacle of the oxygen and hypoxemia disease takes place. Oxygen deficiency can cause prostaglandin, the intersection of leucocyte and three alkene, ergamine, the intersection of angiotensin and 2, inner skin contract active substance of blood vessel increase, make, shrink blood vessel material and relaxation blood vessel material imbalance, cause the lung blood vessel to shrink, the lung circulates resistance to increase, form the artery high pressure of lung. Oxygen deficiency can make the intersection of lung and the intersection of blood vessel and the intersection of smooth muscle and cell membrane strengthen to Ca2 + penetrating, make the intersection of blood vessel and contractivity of smooth muscle strengthen. Arterial blood the intersection of carbon dioxide and partial pressure rise, produce too much H + make blood vessel strengthen to sensitiveness that oxygen deficiency shrink. Various lung pathological changes can also cause the lung capillary bed to reduce, stop up, further make the lung circulate resistance increasing and lung artery high pressure, cause right ventricular hypertrophy, expansion finally. Chronic oxygen deficiency can cause the change of the lung blood vessel configuration. Lung blood vessel shrink, tube wall tension increase and function of growth factor can make the intersection of lung and tiny artery to be wall smooth muscle cell loose, China it is thick for membrane to increase, make, have skin detailed blood vessel week of artery cells are transformed to smooth muscle cells, do not have skin type skin of thin artery (muscularization of arterioles) to form ,It is narrow to be in charge of.
2.Thoracic movement obstacle disease is relatively rare. Serious backbone backside dash for ward and the intersection of backbone and tuberculosis, rheumatoid arthritis, extensive adhesion, thoracic cage of thoracic cage shape the postoperative serious thoracic cage or vertebra deformity caused, can cause thoracic sport to be limited and the intersection of lung and organization press, cause, keep in touch with function obstacle while being restricted, can also cause bigger lung blood vessel to be pressed, twisted, make the lung circulate resistance to strengthen, the artery high pressure of lung thus causes lung worry.
3.Vascular disease of the lung is very rare. Lung arteriolar thromboembolism, primary lung artery hyperbarism substantially as happening repeatedly,etc. can cause the artery high pressure of lung and lung worry takes place.
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