Reason and manifestation and diagnosing _'s general knowledge of protein calm disease of the alveolus

Reason and manifestation and diagnosing _'s general knowledge of protein calm disease of the alveolus
From what reason was protein calm disease of the alveolus caused?
The cause of disease has not been bright, infer that relates to several respect factors: For instance a large amount of dust is sucked (aluminium, oxidize silicons,etc. two times) ,Organism immunological function drops ' Especially infant and pre-school children) ,Inherent cause, get drunk, the microorganism is infected with etc.. And for infect, sometimes very difficult to confirm, send, cause cause of disease to be plain or continue, take place at the intersection of the alveolus and the intersection of albumen and calm disease originally. Such as the virus of big and small afterbirth, the lung sporozoite of card, organizes the afterbirth thick liquid fungus to infect etc. finding that there is calm high protein in alveoluses.
Though it is still indeterminate to start the factor, basically agree that the course is due to lipid supersession obstacle to have illness coming on. Namely because factor function causes metabolic disorder of the pulmonary surfactant in, outside the organism. Up till now, alveolus macrophage vigors to study more one, animal's experiment proves their vigor obviously drops after macrophages engulf the dust, and the patient can make normal cell vigor drop to irritate the macrophage inner particles in lotion, after the bronchus alveolus is irritated and washes and treats, its macrophage vigor of alveolus can rise. Study and has not found Model 2 cells turn into the albumen to increase, the lipoprotein supersession of whole body is not unusual. So generally think a disease drops and has something to do with with removing ability at present.
Which protein calm disease of the alveolus are to behave and how to diagnose?
Clinical manifestation
The clinical manifestation of PAP does not have more specificities, are shown as more gradual advancement has difficulty in breathing, cough, get a cough and glue the phlegm in vain, can accompany and generate heat and cough the suppuration phlegm after continuing and sending and is infected with, it is obviously weak that in addition can behave, the weight is lightened, such whole body symptoms as the appetite fails. Can present the obvious shortness of breath and breathe depletedly in later period. Physical sign usually obvious, can hear while being even and getting wet rale and rotate, pronounce, can appear cyanosis and poke mean later period.
Diagnosis
Diagnose, need in coordination with clinical manifestation, the intersection of radiology and physical sign and organize pathology and/or alveolus irritate lotion can be made a definite diagnosis of while being cytologic to check. Diagnose the basis: Clinical manifestation, for shortness of breath under activity, have, cough occasionally, symptom person who go on aggravate, there are not the bases of infection and blood disease; The chest X-ray can be shown as the filling the air flaky shadow or large stretch of consolidation shadow of little tubercle shadow, spot, HRCT can be seen " The map kind " " pave the way stone kind " Characteristic change; The living fibrous bronchus mirror examines pathology and is checked and full of PAS positive thick granular materials while showing the alveolus, the alveolus can see a large number of amorphous pieces while irritating lotion, often accompany PAS to dye the macrophages of the masculine gender.
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