The gel of Epinephrine treats the effective _'s treatment of malignant tumour of liver

The gel of Epinephrine treats the effective _'s treatment of malignant tumour of liver
Reports such as Frankfort JW Goethe university Vogl of Germany,etc., the injection arranges the gel of platinum Epinephrine while carrying on tumour under the circumstances that CT guides, treating liver malignant tumour has certain curative effect.
Vogl,etc. use purified collagen of ox as the intersection of protein and carrier, add Epinephrine 0.1mg/ml (each time most loud to inject dosage as 1mg) along the intersection of platinum and and 4mg/ml ,Carry on in tumour the injection treats liver malignant tumour. The intravenous bit 500- 1000ml physiological saline first before each injection, in order to reduce the poisonous side effect of whole body of chemotherapy. Then adopt the puncture needle with 6 side holes to carry on the injection in the body of tumour under the circumstances that CT make a reservation.
Vogl,etc. adopt the method 8 of treatment form the intersection of rectal cancer and 17 pieces of liver of patient, shift the cooking stove ' Inject for 5.1 times on average) With 9 primary the intersection of hepatocyte and 13 focuses of hepatocarcinoma ' Inject for 3.1 times on average) . ( Br J Cancer 2002, 86 : 524)
The result reveals, the average volume of shifting tumour before treating is 77.4ml, the focal average volume of primary hepatocarcinoma is 29.2ml. The average volume that treats, shifts the cooking stove is dropped to 68.3ml, and the average volume of the primary hepatocarcinoma cooking stove is dropped to 14.5ml. Treat, follow up a case by regular visits to 6 months, the rate of control treated of part of liver cell cancer is 71%; The rate of control treated of part forming the liver of rectal cancer and shifting the patient is 38%. All patients always accumulate the time of surviving as 13.15 months, it is 14.48 months in life cycle when liver of rectal cancer shift the patient that 8 are formed, the cell cancer patient of 9 cases of liver is 14.11 months. The side effect is mainly transient some pain after injecting ' 76% ) , palpitation ( 24% ) , large sweat ' 30% ) , shoulder ache ' 30% ) , sick to vomit ' 53% ) . Have not obeyed platinum common kidney, ear and peripheral neural toxicity.
The researcher thinks, the part should be better than forming the liver of rectal cancer to shift the cooking stove to inject the curative effect to liver cell cancer of chemotherapy of gel, its reason may be that liver cell cancer generally has membrane of bag, the medicine is difficult to spread beyond tumour, the pressure is relatively high in liver cell cancer at the same time, are favorable to the even diffusion in tumour of medicine.
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