The intersection of Epinephrine and room _ of tachycardia healing solution treatment of can turn back by the intersection of dependence and peaking etc.

The intersection of Epinephrine and room _ of tachycardia healing solution treatment of can turn back by the intersection of dependence and peaking etc.
1.Drug therapy
(1) receptor blocks medicines:
Because originally type the trigger factor of TDP results from increasing in sympathetic nerve activity, the Epinephrine Yes inhibitor can obtain the best curative effect. Or to acute to break out, treat as to treat for a long time, receptor it blocks medicines to be first-selected medicine, heavy dose of general naphthalene Lip river (propranolol) that the daily ability receives Treat, the dosage is: 1- The vein is injected slowly after 2mg dilutes with 5% of the glucose liquid 20ml, if is invalid, use 0.5- 0.75mg, the vein is injected once every 2 minutes, total amount <5mg. Notice general naphthalene Lip river can cause heart decline, aggravate and hypotension, getting aroused in interest and slow, heart park fight etc., observe closely under should attentive cable is guarded. Take orally after the quiet note is effective, the dosage is from 10mg, 3 times d, it is 3mg/kg to rise to the capacity gradually. Generally advocated taking for a long time, should be reduced gradually at the time of decrement, can't stop medicines suddenly. Have report can happen, jump instead after medicines stopped suddenly, can die suddenly while being specific. The tolerance individual of heavy dose of general naphthalene Lip river differs greatly, must pay attention to individuals. Work as and is able to bear not standing, and not reached the patient that capacity, TDP are still breaking out, can select U.S.A. for use and hold Lip river (Metoprolol or beauty suspiciously to fit, double his happy gram) ,Dilute with 5mg first (5% of the glucose liquid 20ml) And then the slow vein is injected, such as being invalid, can repeat once after 5min. Or feel at ease (Nadolol) with naphthalene hydroxy When. It is general naphthalene Lip river with behind can reduce by copy type outbreak number of times or totally if you can't control, break out of TDPs, TU is unusual can return to normal, one is shortened among QTc. But one is still lengthened among some Q-T. The case fatality rate can be reduced from 73% to 6% after treating with general naphthalene Lip river. While employing receptor to block medicines, because the dosage is relatively large, must well monitor, pay attention to the appearance of the bad reaction, correct in time.
(2)Benzene proper Great Britain sodium:
Can be used for being blocked one type TDP that medicine failed to respond to any medical treatment by receptor. The dosage is 50- 100mg, the vein is injected slowly after by injecting the water to dilute, repeat once every 5- 10 minute, until the arrhythmia disappears or accumulates the dosage and reaches 1000mg, the keeping amount of the clothes that correct oneself, the first day 1000mg, the second, 3 days 500mg, 300- 400mg/d later. Serious hypotension, slow and high atrio-ventricular block person in heart failure, aroused in interest forbid. Advocate benzene sodium (35mg) of proper Great Britain With general naphthalene Lip river (150mg) ,Take orally alternatively 3 times d, can also control and break out, a medicine is effectual than to use separately.
(3)Other medicines:
A few cases, to general naphthalene Lip river (inject) Invalid, and use lidocaine or magnesium sulfic acid to be effective. Rice of Vera's handkerchief, general Luo's handkerchief ketone are only specific and effective. Forbid catecholamine and lengthen the medicine replied very much.
2.The sympathetic nerve of left neck cuts off the skill
Persons who fail to respond to any medical treatment to the sufficient medicine, the sympathetic nerve of feasible left neck cuts off the skill. Excise the underpart of the ganglion and the first 3- 5 chest festival (keep the star top of the ganglions of the left star, in order to avoid that Horner syndrome takes place) ,Can make the case fatality rate reduce by 7%. Must take general naphthalene Lip river for a long time after the operation.
3.Plant into the heart and reply the law defibrillating device (ICD)
Can use this method while failing to respond to any medical treatment by above-mentioned two kinds of methods. Evident effect, should install early.
4.The synchronous direct current hits and replies law
As the patient TDP breaks out continuously, the medicine fails to respond to any medical treatment or may develop into the persons who quiver, die suddenly of ventricle, should do and reply law by cable and stop breaking out in time.
5.Classify and pay treating to the defective gene
To LQT1, LQT2 Type (namely KXLQT, MINK and HERG is defective for gene) Patient, should regard potassium passway as " the target is clicked " Treat, such as with Nicorandil (that the potassium passway opens pharmaceuticals) , mend potassium, mend the intersection of magnesium and treatment. Ester is effective too in the spiral shell. To LQT3 type (relevant gene is SCNSA and some HERG) Patient, should regard sodium passway as " the target is clicked " Treat, such as American west law (Mexiletine) . After treating, one, QTc reduce notably among the groups Q-T LQTS3, and group LQTS2 is invalid. As to LQTS2 patient, because it relates to the fact that the potassium density outside cells raise and activate HERG potassium ionophore, supplement potassium, can make, reply very much unusual to correct at this moment.
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