Does the original body of clothing of pneumonia cause _'s general knowledge of atherosclerosis

Does the original body of clothing of pneumonia cause _'s general knowledge of atherosclerosis
The Seattle epidemiologist Grayston of University of Washington in U.S.A. claims, the original body of clothing of pneumonia can cause atherosclerosis. Study to find, all parts of the world have original body of clothing of pneumonia to infect in epidemiology, the majority were infected with 20 years old ago, it is very common too to be infected with repeatedly. Antibody will disappear automatically 3- 5 year after the infection for the first time, but 20 -year-old the intersection of people and the intersection of antibody and positive rate can be up to 50%, will also continue rising later; Old men can be up to 80%; 70% of women. The raised reason is not so obvious, but Grayston thinks, it may be the reflection of male arteriosclerosis with higher incidence.
In 1988 Saikku,etc. found a coronary heart disease patient had obviously higher positive rate of original body serum antibody than the pneumonia clothing of control group, thus link it to coronary heart disease at first. Grayston finds, the narrow person who exceeds 50% of more than 1 coronary artery, the positive rate of antibody is higher than the normal one of angiography notably, and been verified the relevant relation between antibody and coronary heart disease by the test. To come from South Africa and whole U.S.A. include white man, black person, inferior the intersection of state and people and original inhabitants in Alaska add up to the research of 362 one, employ immune cytochemistry (use specific monoclonal antibody of kind) And PCR (polymerase chain reacts) Arteriosclerosis and pathological change and sample waiting for the method to get to corpse examining, operation,etc., including coronary artery, common carotid artery, arteria femoralis, artery and aorta are measured, had not revealed finally that there is age difference of gender. 55% of the arteriosclerosis has original body of clothing of pneumonia while organizing; The electric mirror has also verified its existence, and isolate the original body of this clothing from pathological change. But normal artery and 31 totally without coronary heart disease control group find the intersection of pneumonia and the intersection of clothing and original existence of body in the sample. Have already suffered from porridge a kind of hardened coronary artery or heart to put up a bridge and isolate the original body of clothing of 18 of pneumonia in the blood vessel from 102 now, and further verify that there is original body of clothing alive that exists in pathological change to harden. Two research which Finland and Canada carry on, main atherosclerosis appears behind inoculating a nose of rabbit against the original body of clothing of pneumonia. Inoculate twice the incidence than once is high, but there is no main arteriosclerosis in the control group of the false control group or infection mycoplasma that inoculates. M The main arteriosclerosis model rabbit that hlestein,etc. is induced by cholesterol divides into for 3 times, inoculates original body of clothing of pneumonia, aorta pathological change is obviously aggravated 3 months later. Offer after the 3rd inoculation to very mould persons who usually treat for 7 weeks of A, aorta pathological change is similar to control group, has not aggravated, it is obviously different to treat with the intensity of pathological change of persons who do not treat. Grayston give arteriosclerosis experimental mouse to inoculate clothing, find clothing original body want, exist 20 week at least in aorta behind the original body in the nose, find in pathological change that there is clothing original body, and infect mice to compare with contrasting mice, the pathological change range is obviously great, it has been already 1 time bigger than the control group in 16 weeks. The above-mentioned result of study indicates, the original body of clothing of pneumonia can cause atherosclerosis, and can make the course of pathological change accelerate.
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