Saturday, February 16, 2013

The thorax accumulates the cause of disease of the liquid and _'s general knowledge of pathogenesis

The thorax accumulates the cause of disease of the liquid and _'s general knowledge of pathogenesis
First, cause of disease
1,The infective thorax accumulates the liquid
Common, including the bacterium (tuberculosis fungus is seen at most) , the fungi, parasite, pathogen causes mycoplasma and virus,etc., such as tuberculosis exudative pleurisy, tuberculosis empyema, non- specific empyema, pleura actinomycetes disease, white bead fungus disease of the pleura, * amebic disease of the pleura, lung fluke pleurisy,etc..
2,The malignant thorax accumulates the liquid
It can be a pleura ' Primary) Or other the intersection of position and pleura of malignant tumour shift ' Then sending) ,The most common transformation cancer comes from lung cancer, breast carcinoma, ovarian cancer, gastric carcinoma and lymphoma,etc., primary pleura malignant tumour is cover tumour among the pleura.
3,Disease and allergy disease of connective tissue
In desmosis such as systemic lupus erythematosus, rheumatoid arthritis, systemic scleroderma, leather myositis,etc. can accumulate the liquid with the thorax, still have a liking for acid grains of cell increasing pleurisy, syndrome,etc. after myocardium infarction.
4,Other reasons
For instance the Mi thorax of cholesterol pleurisy, milk accumulates the liquid, hemothorax, blood pneumothorax, leaking thorax accumulate the liquid etc..
Second, pathogenesis
In the normal pleura is the negative pressure, include protein in the liquid of chest, there is colloid that permeates and presses, PH and candy content are similar to number value in the blood. The blood supplt of one storey of pleuras of wall mainly comes from the systemic circulation, its quiet water pressure is high, and the dirty layer of pleuras blood is for the greater part to come from the lung circulation with lower quiet water pressure, it is the same that the colloidal infiltration in two layers of pleuras capillary is pressed, the liquid in the pleura was produced by one floor of pleuras of wall finally, and one pair of dirty storey of pleurases was gone back to absorb, often in dynamic equilibrium, 35%~75% chest liquid is changed per hour, calculate from animal's experiment: The mankind nearly has 0.5~1L liquid to support through normal flow and blood of pleura of this kind of liquid in the pleura every day, the lymphocytic factor of guiding etc. has close relations, protein enters the pleura from surface of two floors of pleuras, and then absorb by the lymphatic vessel, nearly there is 0.25~0.5L lymphocytic liquid that is touched one of lymphatic vessels by the chest and entered the chest conduit every day, the ones that hindered liquid and protein of thorax in any reason are back to absorb, causes the thorax to accumulate the liquid in the distant relative, thorax accumulate liquid according to different property their, can divide into, leak liquid, ooze out the liquid, hemothorax, empyema, the chyle chest,etc.. The intersection of pleura and inflammation can make the intersection of blood vessel and the intersection of wall and penetrating the intersection of and increase, more people of protein ease the intersection of pleura and, make chest protein accumulate the liquid, cause the thorax to accumulate the liquid in the liquid. Low albumen blood disease that pulse reason of liver cirrhosis,etc. caused on the door. Colloid ooze, press, reduce in the blood, thorax it accumulates liquid to be can for leak liquid, or superior vena cava getting obstructive, make quiet water pressure rise in the blood vessel, can also appear the thorax accumulate liquid, the chest conduit is obstructed, form the chyle chest.
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