Pathological diagnosis _'s treatment of the plump type myocardium disease

Pathological diagnosis _'s treatment of the plump type myocardium disease
Plump type myocardium disease is plump as the characteristic with the cardiac muscle. Can be divided into obstructing (Obstructive) while flowing out one and obstructing according to the left ventricle With the not obstructing (Non-obstructive) Plump type myocardium disease, unsymmetry interventricular septum plump to cause the intersection of aorta and petal lay getting narrow to claim special getting plump hair aorta one downed narrowly (Idiopathic hypertrophic subaortic stenosis IHSS) .
Cause of disease
Not clear, perhaps the factor is as follows,
First, heredityThere can be many people to have illness coming on in a family, it relates to heredity to point out. Matsumori finds a disease HLADRW4 detection rate is up to 73.3%, the control group detection rate is extremely low. HLADR system is one of the hereditary genes, there is regulating action on immunoreaction, prove a disease relates to heredity.
Second, the endocrine is disorderlyHave a liking for the intersection of junket and the intersection of cell and compatible getting plump more myocardium patient, patient of tumour, human vein instil, send to myocardium necrosis by a large amount of noradrenaline. The intersection of animal and experiment, can cause the cardiac muscle to be plump while being intravenous to instil the catecholamine. Therefore someone thinks the plump type myocardium disease results from the reason that the endocrine is disorderly.
Pathology
A bottom interventricular septum and papilla skin is the most obvious in pathological change plump for cardiac muscle that main, especially aorta, therefore form the left ventricle and flow out one and obstruct. The ventricle often shrinks and takes the form of S -shaped crack, the interventricular septum thickness and left thickness proportion of room wall are greater than 1.5 o'clock, called the interventricular septum of unsymmetry plumply. The plump position of cardiac muscle is especially represented in apex of the heart department and heart other positions person too, myocardium cells are loose, it is disorderly to arrange, change for pathology of this disease. When having prominent bicuspid valves not to close completely, can have then the sending bicuspid valve leaf increases thick.
First, symptomThere is a prominent difference among men and women of this disease, mostly symptom appears at 30-40 years old, increase with age, symptom is more obvious, there are main symptoms Having difficulty in breathing, the labour has difficulty in breathing, present and sit up straight and breathe or popping seriously to have difficulty in breathing at the night, because plump cardiac muscle comply with, reduce, left ventricle pressure increase latter stage such as relaxation, and then the left room pressure increases, produce due to lung extravasated blood. Angina pectoris; Often have typical angina pectoris, break out after the labour. Chest ache duration to be relatively long, suck, take, be invalid and can aggravate with Nitroglycerin. Outbreak of angina pectoris, may detailed coronary artery it pigeonholes into myocardium blood supply to be enough in the plump cardiac muscle, and the cardiac muscle is plump and aerobic to increase. Faint and dizzy; Happen when fatigue more, happen angry to make not quite clear, because left ventricle comply with reduce perhaps, orthosympathetic after fatigue the function of muscular strength of the sex is strengthened, it is worse to cause the left ventricle, the intersection of relaxation and issues of blood plentiful and less ventricle, left room flow out line obstruct, aggravate, heartbeat producing amount reduced, cause the blood supply of brain to be insufficient, or because of excessively stimulating the receptor of pressure of left ventricle, cause the diastaltic blood vessel to expand. Blood pressure drops, when the speed takes place or pass the slow arrhythmia, can also cause and faint and dizzy. Palpitation; The patient feels the heart beats strongly, especially lie on the left side in the location more obvious, may be caused by changing in arrhythmia or heart function.
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