Pathology of the plump type myocardium disease and physiological _'s general knowledge of the pathology

Pathology of the plump type myocardium disease and physiological _'s general knowledge of the pathology
Main pathology is varied to the cardiac muscle of left room plumply, becomes narrow, often increase with the bicuspid valve leaf thick in the room. Can be seen the myocardium fiber thick and interlocking and arranging under the microscope. Because room wall plump range and intensity different, divide disease this into three type: The asymmetric interventricular septum is plump, accounts for 90%; The symmetrical left ventricle is plump, accounts for 5%; The special position is plump: Account for 3% apex of the heart,interventricular septum later and side part is plump to last l%,there are plump to account for 1% on in the middle part of ventricle.
Because the interventricular septum obviously increases high calcium in thick and myocardium cells, make the cardiac muscle strengthen the catecholamine reactivity, cause the high motive force shrink of skin of ventricle, the left room flows out a blood flow to accelerate. Because this place produces the negative pressure effect, move before attracting the frontal lobe of bicuspid valve to be obvious, close to the interventricular septum, cause left room further narrow to flow out line and bicuspid valve close completely, form left room flow out dishes of systolic phase pressure steps poor. It can cause the recurrent tension of room wall to increase and increase with the myocardium oxygen demand that the pressure steps are bad, cause ischemic necrosis of the cardiac muscle and fiber, thus form the vicious circle and cause heart failure.
Because the aorta diastolic pressure lower, relaxation of left room is pressed and increased at the end, coronary artery is thereupon full of reducing, make the blood in the ventricle wall reduce. Systolic phase load increases, make relaxation full of time to postpone, becomes narrow to make the left room full of load to reduce in the room, myocardium the intersection of fibrin and unusual hyperplasia make cardiac muscle go, shrink performance, reduce, quality fiber increase and muscle fibre arrange disorder make the intersection of room and the intersection of wall and stiff degrees of increase among the cardiac muscle, thus reduce the relaxation speed of ventricle and influence the ventricle relaxation function.
|