Plump type myocardium disease _'s symptom of pathological diagnosis

Plump type myocardium disease, _'s symptom of pathological diagnosis
What is meant by plump type myocardium disease


Plump type myocardium disease is plump as the characteristic with the cardiac muscle. Can be divided into obstructing (Obstructive) while flowing out one and obstructing according to the left ventricle With the not obstructing (Non-obstructive) Plump type myocardium disease, unsymmetry interventricular septum plump to cause the intersection of aorta and petal lay getting narrow to claim special getting plump hair aorta one downed narrowly ( Idiopathic hypertrophic subaortic stenosis IHSS) .

Cause of disease

Not clear, perhaps the factor is as follows,

First, there can be many people to have illness coming on in a family of heredity, it relates to heredity to point out. Matsumori finds a disease HLADRW4 detection rate is up to 73.3%, the control group detection rate is extremely low. HLADR system is one of the hereditary genes, there is regulating action on immunoreaction, prove a disease relates to heredity.

Second, endocrine disorder have a liking for compatible plump type myocardium patients of tumour patient of junket cell more, the human vein instils a large amount of noradrenaline and causes myocardium necrosis. The intersection of animal and experiment, can cause the cardiac muscle to be plump while being intravenous to instil the catecholamine. Therefore someone thinks the plump type myocardium disease results from the reason that the endocrine is disorderly.

Pathology

A bottom interventricular septum and papilla skin is the most obvious in pathological change plump for cardiac muscle that main, especially aorta, therefore form the left ventricle and flow out one and obstruct. The ventricle often shrinks and takes the form of S -shaped crack, the interventricular septum thickness and left thickness proportion of room wall are greater than 1.5 o'clock, called the interventricular septum of unsymmetry plumply. The plump position of cardiac muscle is especially represented in apex of the heart department and heart other positions person too, myocardium cells are loose, it is disorderly to arrange, change for pathology of this disease. When having prominent bicuspid valves not to close completely, can have then the sending bicuspid valve leaf increases thick.

First, there is a prominent difference among a disease men and women of symptom, mostly symptom appears at 30- 40 years old, increase with age, symptom is more obvious, there are main symptoms Having difficulty in breathing, the labour has difficulty in breathing, present and sit up straight and breathe or popping seriously to have difficulty in breathing at the night, because plump cardiac muscle comply with, reduce, left ventricle pressure increase latter stage such as relaxation, and then the left room pressure increases, produce due to lung extravasated blood. Angina pectoris; Often have typical angina pectoris, break out after the labour. Chest ache duration to be relatively long, suck, take, be invalid and can aggravate with Nitroglycerin. Outbreak of angina pectoris, may detailed coronary artery it pigeonholes into myocardium blood supply to be enough in the plump cardiac muscle, and the cardiac muscle is plump and aerobic to increase. Faint and dizzy; Take place when fatigue more, take place mechanism to be not quite clear, because left ventricle comply with reduce perhaps, orthosympathetic after fatigue the function of muscular strength of the sex is strengthened, it is worse to cause the left ventricle, the intersection of relaxation and issues of blood plentiful and less ventricle, left room flow out line obstruct, aggravate, heartbeat producing amount reduced, cause the blood supply of brain to be insufficient, or because of excessively stimulating the receptor of pressure of left ventricle, cause the diastaltic blood vessel to expand. Blood pressure drops, when the speed takes place or pass the slow arrhythmia, can also cause and faint and dizzy. Palpitation; The patient feels the heart beats strongly, especially lie on the left side in the location more obvious, may be caused by changing in arrhythmia or heart function.

Second, common physical sign of physical sign The systolic phase of apex of the heart department beats; Because the cardiac muscle is plump, it is obvious that beats to strengthen. Because the left ventricle is reduced, the atrium shrinks and strengthens, the blood flow strikes the left ventricular wall, excited before there can be systolic phase in the apex of the heart department. Last the second systolic phase to beat after the first sound, form systolic phase and beat doubly. Systolic phase is thin to tremble; In the apex of the heart department more. There are thin persons who tremble of systolic phase, it is more relatively heavy that left ventricle flows out one and obstructs. Systolic phase noise; Present on the brestbone left bottom flange or inside of apex of the heart " The coarse drying " The noise in later period, is caused by the fact that the left ventricle flows out one to obstruct while shrinking. The factor strengthening myocardium contractile force or reducing artery resistance, can make the pressure difference between left ventricle and aorta increase, the noise is strengthened, the factor can reduce myocardium contractile force or increase artery resistance ing, can make the pressure steps reduce badly, the noise is weakened. When the energies of going back amount increase, the noise is weakened. Energies of answering quantity reduces the noise to strengthen. Systolic phase noise of apex of the heart department; About 50% of this disease can not be closed completely with the bicuspid valve, therefore the apex of the heart department has later period noises while shrinking, or the whole systolic phase noise. Third heart sound and fourth sound.

(1) The X-ray examination heart is normal in size or increases, it is the direct radio that the pressure rank that heart size and heart and left ventricle shed during one is bad, the pressure steps are bad big, also the bigger the heart is. It is a main fact that the heart left ventricle is plump, the aorta is not increased widely, the lung artery section is not obviously outstanding, lung extravasated blood is mostly relatively light, the calcification of common bicuspid valve.

(2) Electrocardiogram because heart ischemic, it is extremely unusual for cardiac muscle to reply, it is common for ST-T to change, left ventricle plump and the intersection of Left deviation and bunch prop up block, more meet too, perhaps because Q wave appears in the plump and myocardium fiber of interventricular septum, this disease often has all kinds of arrhythmia.

(3) The interesting picture of the supersound is that a important one is not the invading diagnostic method. Mainly behave and have The interventricular septum unusually increases thick, thickness of interventricular septum at the end of term of relaxation> 15mm. The interventricular septum moves the range is obviously reduced, is generally less than or equal to 5mm. The thickness ratio of the wall can be up to behind the interventricular septum thickness left room 1.5-2.5:1, have already diagnosed meanings in ratio that it is generally acknowledged> 1.5:1. The left ventricle shrinks the internal diameter of the end smaller than normal people. Shrink the initial time room to separate and often obviously shrink with the distance of the bicuspid valve frontal lobe. The bicuspid valve gets the interventricular septum near, stop before the second sound to sports before systolic phase. The aorta shrinks in middle period, shuts off, may shrink the early blood flow fast, the speed of blood flow was slowed down suddenly because of obstructing and aggravating to shrink on later stage, produced the gravitation (Ventureeffect) Due to. The analysis that the above 7 items should be comprehensive, can draw the correct conclusion, should pay attention to essential hypertension, the thyroid gland function bows, can cause and behave similarly.

(4) The heart conduit check and the cardiovascular vessel radiography heart conduit check, left ventricle and left ventricle appear in the pressure steps badly while flowing out one, left ventricle pressure increase latter stage such as relaxation, pressure steps flow out with left ventricle dish obstruct intensity is the positive correlation while being bad. The radiography of cardiovascular vessel, when interventricular septum muscles are plump and obvious, it is obvious the ventricle is presented narrow and long crack kind and changed, to diagnosing meaningfully.

Diagnosis

Blue and green middle aged labour angina pectoris, the Nitroglycerin can't be relieved, died suddenly in the family
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