's general knowledge of fatty liver

's general knowledge of fatty liver
Total the intersection of lipoprotein and quantity under normal liver of people, account for 5% that liver weigh, include phosphatide, triglyceride, the intersection of lipoprotein and acid, cholesterol and cholesterol lipoprotein. And the person who suffers from fatty liver, total lipoprotein quantity can be up to 40%-50%, triglyceride and lipoprotein are sour, and phosphatide, cholesterol and cholesterol lipoprotein increase only on a small quantity. First, pathogenesis After the fat of food is digested by hydrolase, its chyle particle (main component is triglyceride) Absorbed into the blood by the cover on the small intestine. The chyle particle which enters the blood has three pieces of outlet: First, the energy called muscule activity, second, store as the potential energy in the adipose tissue after decomposing, third, transship and carry on the supersession to the liver. Lipoprotein is combined into lipoprotein (VLDL) of extremely low density to have a change of luck until triglyceride and year of the liver The particle is secreted into the blood. If triglyceride person who produce, more, or extremely low density lipoprotein quantity little, cause triglyceride to pile up in the liver, and form fatty liver. Second, cause of disease 1. Drink. It is a common cause of disease of causing fatty liver to drink, drinking causes fatty liver to be that alcohol have direct toxic function on supersession of triglyceride in the liver. Health person, drink and include 100-200 grams of ethanol every day, 10-12 days continuously, whether its diet includes protein, fatty liver can happen, low protein is only that one kind aggravates the factor. 2. Hunger. Because blood glucose is reduced, fatty acid in fatty liver is organized is passive to enter the blood, make the free fatty acid in the blood rise, there is medium-sized degree of fat that is piled up in the liver. 3. Malnutritive. Because protein is scarce, and lead to the fact lipoprotein of extremely low density is formated and reduced, lead to the fact liver transship triglyceride the obstacle takes place, the fat is piled up in the liver like this. 4. Fat. 50% of the overweight persons have fatty infiltration in liver, this is because the adipose tissue increases, the free fatty acid is released and increased. Fatty liver is reduced because of ingesting too many, movement after hepatitis, in addition liver function not full restoration, it is extremely apt to lead to the fact the fat is accumulated in the liver memory. Because chronic hepatitis patient increases nutrition and reduces the physical exertion inappropriately, also often with fatty liver. 5. Diabetes. Nearly have half diabetic patient with fatty liver, this is because of the diabetic patient, glucose can't be utilized, cause three major supersession to be disorderly, it causes fatty liver to make fatty acid accumulate in the liver memory finally. 6. Cortical hormone. It make people fat and fatty liver happens to use hormone for a long time. 7. Tetracycline. Can cause fatty liver, in pregnant woman, cause with the intersection of gestation and acute fatty liver displaying similar fatty liver often, mortality is up to more than 75%. Third, clinical manifestation Light fatty liver can have any symptom, or CT check etc. find through B -type supersound only. After fatty liver takes shape, or secret anguish that the majority displays losing the appetite, disgusting, vomiting, weight and drops, weak, uncomfortable in abdominal distension, liver district, third amino acid transaminase (ALT) Raise, a few patients can present slight jaundice. The physical examination can touch the swelling liver (generally within 2-3 centimetres under right rib) ,The surface is smooth, the edge is round and blunt, the soft or medium-sized hardness of the texture, there can be slight tenderness, some patients knock and hit aching. The serious disease patient can present liver cirrhosis and behave. Fourth, diagnose The diagnosis of fatty liver mainly relies on the medical history, clinical manifestation and laboratory to check, especially Ultrasonography B and CT can find early fatty liver, but make a definite diagnosis of and depend on the liver to live and examine. 1. Medical history. There is Chinese liquor drinking (especially alcohol with high content for a long time) , fat, diabetes, malnutrition and poisoning liver damage the medical history. 2. Clinical manifestation. Or secret anguish that losing the appetite, sick, weak, liver district is uncomfortable. It is smooth that can be seen on hepatomegaly, surface at the time of the physical examination, touch a tender spot or knock and hit aching bluntly and slightly round on the edge. 3. Check in the laboratory. Liver function ALT is normal or rises, there is high lipoprotein blood disease that behaves, triglyceride rises, serum - GT rises actively, electric swimming blood plasma globulin of albumen increases. 4. Supersound and CT. The B -type supersound reveals the liver increases, the essence presents the dense strong reflection luminous point, the deep department organizes the echo to decay. CT scans and reveals the liver density than other essence internal organs (such as the spleen) Low. 5. The liver is examined vivid. Confirm the basis. Fifth, treat It is to remove the cause of disease to treat the principle, adjust the diet, increase sports, use medicine rationally. 1. Remove the cause of disease. Remove all factors that can cause fatty liver. Stop drinking and employ the high protein diet, can often reduce the fat in the liver effectively. Alcohol fatty liver to stop drinking mainly, pay sufficient protein diet, make the fat piled up in the liver remove effectively; The overweight person wants to reduce weight; The diabetic patient should treat to have illness coming on originally. 2. Adjust the diet. This treats an important link of fatty liver. The diet needs high protein, right amount of fat and carbohydrate. 3. Increase the amount of exercise. According to different having illness coming on originally and can do exercises in right amount, accelerate the supersession of the fat. 4. Use medicine rationally. Can explain, take, go the intersection of lipoprotein and medicine and reduce weight medicine by some according to medicine, the therapeutic effect is not very definite. The rational administration can reduce transaminase, make liver function return to normal, but these medicines mostly diminish the side effect of the liver, should notice while using.
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