The fatty liver patient selects the medicine _ for use to treat cautiously
1. Lower medicine of fat of blood and liver to damage: High lipoprotein blood disease is probably liver disease, especially a sign of fatty liver and fat hepatitis. The liver appearing after this kind of case is by lowering medicine of fat of blood damages the manifestation that is mostly the original hepatopathy, have some patient to lower the intersection of fat of blood and medicine, bring out too, because majority lower medicine of fat of blood promote lipid in the blood to transport to the liver and excrete the supersession, and fatty liver is often with lipid supersession obstacle of liver.
Elastic enzyme and man of chlorine shellfish ester,etc. lower the intersection of lipoprotein and medicine, employ improper and extremely apt to cause liver damage with the fat of liver depositing and aggravating; Nicotinic acid and derivative,etc. have report that liver damage too, long-term administration appear the intersection of door and pulse and the intersection of fiber and take and the intersection of fiber and cholangitis of taking etc. around the the intersection of door and pulse even; Dextrorotation thyroxine, third cube phenol,etc. have certain poisonous side effects on also liver to lower the medicine of fat of blood; Much alkene unsaturated fatty acid such as the fish oil can aggravate the big mouse's alcohol liver to damage; HMGCoA reductase inhibitor can cause acute bile depositing hepatitis and transaminase to rise.
2. Lower the beneficial function on fatty liver of medicine of fat of blood: It is unusual to cut down liver function that his man can improve alcohol fatty liver hard notably and fat of blood, and curative effect has no relations with whether the patient amalgamates HCV and infects. Someone general to cut down the intersection of he and man, try out on 2 primary bile liver cirrhosis, result raised competence, Tcho of blood plasma, be taken the form of, dropped greatly, liver function is also improved to some extent. It is relatively safe to point out HMGCoA reductase inhibitor even if it is a patient of the history to there is hepatopathy or drinking. Animal experiment show, general to cut down the intersection of he and man, have on fatty liver model that the high lipoprotein diet induces, prevent and cure function while being sure.
And can inhibit from high lipoprotein blood disease fatty liver rabbit liver fine to dissolve the intersection of zymogen and the intersection of activator and the intersection of inhibitor and excessive expression of gene while being general to cut down the intersection of he and man, lucky non- Qi, nicotinic acid Luo medicine, HMGCoA reductase inhibitor can also inhibit the hyperplasia of HSC. It may contribute to preventing and curing little thrombosis and emergence of fat hepatitis and fiber to point out and fall the treatment of fat of blood. In addition, there is the fish oil on some medicines and fatty liver due to high lipoprotein diet to prevent and cure function certainly; And, the appropriate one lowers the drug therapy of fat of blood to the primary high lipoprotein blood disease patient, really give consideration to and reduce the fat of blood and prevent and cure the efficiency of fatty liver.
3.The adaptation card lowering the medicine of fat of blood and is used in fatty liver: The fatty liver patient should select for use and lower the medicine of fat of blood cautiously. Needn't lower the medicine of fat of blood with the fatty liver patient of the high lipoprotein blood disease in principle; Alcohol fatty liver with high for lipoprotein blood for disease,best treatment to stop drinking, do not generally need to employ and lower the medicine of fat of blood; Obesity, diabetes fatty liver with high lipoprotein blood disease,unless coronary heart more disease at the same time, after otherwise only to keeping on a diet, increasing sports and treating and having illness coming on for 3 months originally, the fat of blood is unusually person sustained ' The blood plasma Tcho is greater than 6.46mmol/L and/or low density lipoprotein cholesterol and greater than 4.13mmol/L, three ester acyl glycerine and greater than 2.26mmol/L) ,The ones that just for corresponding having a little effect on liver functioned lowered the medicine of fat of blood; Fatty liver due to primary high lipoprotein blood disease can employ and lower the medicine of fat of blood on the basis of complex treatment, but take appropriate safe index of reducing medicine quantity and monitoring liver function etc., unite and use protecting the liver medicine if necessary, or is damaged and corrected in the liver and then lower the treatment of fat of blood again.
4. Lower the rational choice of the medicine of fat of blood: Though some high lipoprotein blood disease fatty liver patients need to accept that lower the fat of blood to treat, but how to still have a common understanding to lower the medicine of fat of blood to select for use. The acid of gallbladder combines the resin, because the absorption of intestinal vitamin of influence with peculiar smell, and may aggravate Senior Three ester's acyl glycerine blood disease, is not suitable for treating fatty liver; Dextrorotation thyroxine, elastic enzyme, nicotinic acid and derivative, because there are more bad reactions or lower the function of fat of blood limitedly, treatment not used for high lipoprotein blood disease and fatty liver generally too.
Chlorine shellfish's cube ester in benzene oxygen second and all kinds of acid because the side effect is great, have already used few now; Benzene pitches shellfishes specially, not luckily Luo Qi,etc. have relatively young side effect, but the prudent fatty liver patient used for three ester acyl glycerine of blood plasma obviously increasing, appear the intersection of liver function and prominent unusually, myositis, cholelithiasis and treat situation such as being invalid park medicines in time 3 month in the course of treatment. HMGCoA reductase inhibitor used mainly in with the fatty liver patient of high cholesterol blood disease, employ relatively safe a short time, like, have, prevent and cure function while being sure to fatty liver, but long term administration or Luo Qi,etc. take jointly, needs to consider its potential liver, kidney and muscle toxicity with nicotinic acid, lucky.
Security and curative effect of much alkene unsaturated fatty acid preparations such as fish oil, wait the great series are employed and criticized of a text for a long time, and it may not be beneficial to fatty liver patient not stopping drinking. Taurine although and fatty liver have prevent and cure function to high the intersection of lipoprotein and diet and/or high the intersection of lipoprotein and the intersection of blood and disease that alcohol induce, but only there are its valid clinical trial reports of a confirmation so far.
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