Pancreas cancer and clinical feature _ symptom
Often can make a definite diagnosis of pancreas cancer at disease in later period. The common clinical feature has weight lightening, abdominal pain and jaundice. It is a kind of non- specific symptom that the weight is lightened, it is usually gradual advancement, begin to happen promptly before confirming pancreas cancer several months. 65%- 80% of the patients suffer from abdominal pain, often more serious to the night. It is flat to poach location and seat to make pain become more serious. Pain often smudgy, difficult to explain, this kind of situation often delayed diagnosing.
Jaundice is the third most common symptom, a lot of patients relatively appear late. Jaundice whom person who go on aggravate usually, have, present, fluctuate state naturally too. To the patient of little pancreas cancer near the total bile duct, jaundice is the only clinical manifestation. So, should assess such jaundice different to explain carefully. Often this kind of tumour is easier to excise. Jaundice and often annoying pruritus with upper arm, shank and belly, especially aggravate at the night. Pruritus relates to bile salt retention of skin. Because the relations of bile salt level and pruritus intensity are closer than level of serum bilirubin in the skin. And other statements, the bile salt has promoted the release of protease in the cells around, and the protease can cause pruritus, but not every patient's pruritus of main suit. May see pruritus and appear before jaundice on clinic happen once in a while. Though painless jaundice is still declared to the pancreas cancer patient's characterized symptom improperly, but the patient who there is this kind of behavior in fact is a kind of exception.
Non- specific physical sign with symptom, pancreas of cancer include apocleisis, up the intersection of and cholangitis, change (constipation, suffer from diarrhoea, it is bad to absorb, the bloated air of stomach, or the bloated air of intestines) that it is used to and defecating . Diabetes can be following breaking out. Because the stomach, pylorus or duodenum are encroached on directly, or the disorder of the stomach function, can erupt symptom that the stomach empty the obstacle simultaneously. Transformation thrombus phlebitis (Trousseau physical sign) usually correlated to lung cancer Also may be the early physical sign of pancreas cancer. The middle-aged person can present the melancholia, doubt disease and hysteria, it is generally acknowledged it is caused by pancreas cancer. Can see the spiritual symptom relying mainly on depressed symptom in the pancreas cancer patient too once in a while. This kind of patient with spiritual symptom is early 6 months than the appearances of physiological physical sign and symptom for more than half its spiritual symptom proportion. Just because there are a lot of non- specific and fuzzy physical sign and symptom, so the early diagnosis of pancreas cancer is very difficult, doctors must maintain sharp vigilance.
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